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DNA lab: useful links

This is a list of additional resources for the DNA lab theme and information sheets.

DNA extraction

DNA extraction animation
An interactive showing the steps of DNA extraction, from Learn.Genetics – an online Genetics Science Learning Centre run by the University of Utah.

Restriction enzymes

Examples of restriction enzymes and their recognition sites
This is an animation showing how restriction enzymes work.

A closer look at restriction enzymes
A detailed explanation of restriction enzyme activity, including specific examples, developed by Colorado State University.

DNA ligation

A closer look at ligation
A detailed explanation of ligation, including scientists proving that DNA fragments have been joined together by ligation. Developed by Colorado State University.

Bacterial transformation

Bacterial cell structure
Get to know more about what’s inside a bacterial cell, from CELLS alive!

DNA, plasmids and bacterial transformation
Examples of plasmids that are used in the laboratory for bacterial transformation, from Dr John Kimball at Harvard University.

Bacterial transformation
A step-by-step guide to doing a bacterial transformation in the lab, from Plattsburgh State University of New York.

Making recombinant DNA in the classroom
A cut and paste activity to demonstrate recombinant DNA in the classroom.
A video resource demonstrating how to make recombinant DNA.

Polymerase chain reaction (PCR)

Polymerase chain reaction animation
An interactive showing the steps of PCR, from Learn.Genetics – an online Genetics Science Learning Centre run by the University of Utah.

Gel electrophoresis

Gel electrophoresis (Colorado State University Biotechnology Index)
This site provides an excellent explanation of gel electrophoresis and has a link to a very good interactive activity for senior biology students.

DNA sequencing

The University of Michigan DNA Sequencing Core
An excellent explanation of the Sanger (di-deoxy) DNA sequencing method, with very clear diagrams.

Microarrays/DNA chips

Anatomy of a comparative gene expression study
Detailed explanations about how microarrays are made and used, in very user-friendly language.


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